Description
Technical Monograph: ADX-05 | Adamantane-Modified Neuropeptide
Product Code: HRL-ADX-05 | Total Peptide Mass: 5 mg
This high-purity synthetic neuropeptide is an advanced derivative of the Semax (ACTH 4-10) sequence, featuring a unique C-terminal Adamantane modification. Engineered for high-resolution neurological research, this 5 mg variant is optimized for investigating the upregulation of neurotrophic factors and the modulation of dopaminergic signaling with enhanced metabolic stability.
Molecular Specification & Composition
| Attribute | Technical Detail |
| Sequence Base | ACTH (4-7) Pro-Gly-Pro |
| Modification | C-Terminal Adamantyl-Moiety |
| Purity (HPLC) | >99.0% |
| Total Mass | 5 mg Lyophilized Powder |
Analytical Characteristics
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Enhanced Lipophilicity: The Adamantane group is specifically engineered to increase the peptide’s affinity for lipid membranes, facilitating high-resolution data collection in blood-brain barrier (BBB) transport models.
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Neurotrophic Induction Research: Formulated to study the potent upregulation of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) in vitro.
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Structural Longevity: The unique molecular architecture ensures superior resistance to peptidases, providing an extended observation window during neuro-signaling simulations compared to linear ACTH analogs.
Laboratory Application Fields
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Neurogenesis Modeling: Investigating the proliferation and differentiation of neural progenitor cells in the hippocampus.
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Synaptic Plasticity Research: Analysis of the peptide’s influence on long-term potentiation (LTP) and dendritic branching.
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Dopaminergic Signaling Studies: Evaluation of the interaction between ACTH-analogs and D2/D3 receptor expression in neural cellular models.
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Neuroprotective Pathway Mapping: Studying the peptide’s impact on cellular survival during hypoxia or oxidative stress simulations.
Storage & Handling Protocols
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Thermal Management: Store lyophilized vials at -20°C for maximum molecular integrity.
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Reconstitution: Maintain at 2-8°C post-reconstitution. This Adamantane-modified sequence is more stable than standard neuropeptides but should still be protected from direct UV exposure and high-frequency agitation.
IMPORTANT NOTICE & DISCLAIMER
FOR LABORATORY RESEARCH USE ONLY. This product is a synthesized chemical reagent intended solely for in vitro laboratory research and analytical testing. It is NOT a drug, food, or cosmetic, and it is NOT intended for human consumption, inhalation, or any form of internal or external application to humans or animals.
Any use of this product outside of a controlled laboratory setting is strictly prohibited. The purchaser assumes all responsibility for the handling, storage, and regulatory compliance of this compound. Hudson Research Lab does not provide medical advice or instructions for human application. Keep out of reach of children.
