Description
Product Name: BPC-157 (Bepecin) Molecular Formula: C62H98N16O22 Molar Mass: ~1419.5 g/mol Sequence:Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Product Overview BPC-157 is a partial sequence of the “Body Protection Compound,” a protein found naturally in the stomach. Unlike many other peptides, BPC-157 is exceptionally stable in gastric juice and resistant to hydrolysis. Its stability and lack of toxicity in animal models have made it a primary candidate for research into tissue regeneration. It is often studied alongside thymosin beta-4 (TB-500) for its complementary effects on tissue repair.
Mechanism of Action The precise mechanism of BPC-157 is multi-faceted, involving several signaling pathways:
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Angiogenesis (VEGF Upregulation): Research indicates BPC-157 stimulates the expression of Vascular Endothelial Growth Factor (VEGF), promoting the formation of new blood vessels (angiogenesis). This increased blood flow is critical for tissue repair.
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Nitric Oxide (NO) Modulation: It interacts with the nitric oxide pathway to regulate endothelial function and protect tissue from ischemic damage.
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Fibroblast Migration: The peptide facilitates the migration of fibroblasts to sites of injury, which accelerates collagen synthesis and structural repair.
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Anti-Inflammatory Action: It has been shown to modulate the inflammatory response, reducing edema and oxidative stress in damaged tissues.
Research Applications BPC-157 is a versatile compound in regenerative medicine research, with key applications including:
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Musculoskeletal Repair: Accelerating the healing of transected rat Achilles tendons, muscle tears, and ligament damage.
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Gastrointestinal Health: Investigating the repair of intestinal anastomosis, treatment of fistulas, and protection against NSAID-induced gastric ulcers or inflammatory bowel disease (IBD) models.
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Bone Healing: Studies focusing on the peptide’s ability to improve bone defect healing and mitigate osteoporosis in animal models.
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Neuroprotection: Emerging research into the peptide’s influence on the gut-brain axis and potential neuroprotective qualities following traumatic brain injury (TBI).
Storage and Handling
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Storage: Store lyophilized powder at 2-8°C. Protect from moisture and light.
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Stability: Stable for 2 years when stored properly in lyophilized form. Reconstituted solution is stable for up to 4 weeks at 4°C.
Disclaimer: This material is sold for research and development purposes only. It is not intended for human ingestion, diagnostic, therapeutic, or clinical procedures. All research must be conducted by qualified professionals in a laboratory setting.
