Description
Selank (5 mg)
Product Name: Selank
Molecular Formula:
Molar Mass: ~751.9 g/mol
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro (Tuftsin analog)
Product Overview
Selank is a synthetic heptapeptide and a derivative of the naturally occurring tetrapeptide Tuftsin. It was developed to serve as a stable, long-acting anxiolytic (anti-anxiety) and nootropic agent. While it shares many functional goals with Semax, Selank is unique because it combines potent stress-reducing capabilities with immunomodulatory properties, making it a “calming nootropic” that supports the body’s natural defense systems.
Mechanism of Action
Selank operates through a complex interplay of neurotransmitter and immune pathways:
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GABAergic Modulation: It acts as a positive allosteric modulator of GABA-A receptors, enhancing the inhibitory effect of GABA. This provides a calming, anti-anxiety effect similar to benzodiazepines, but without the risks of sedation, motor impairment, or dependency.
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Enkephalin Stabilization: It inhibits the enzymes that break down enkephalins (natural opioid peptides). This helps prolong the body’s natural “feel-good” and pain-relief signals, contributing to its anti-stress profile.
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Monoamine Balance: Research shows it influences the metabolism of serotonin and dopamine in the brainstem, helping to stabilize mood and improve focus during periods of psychological pressure.
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Immunomodulation: Since it is derived from Tuftsin (part of IgG), Selank can influence the production of Interleukin-6 (IL-6) and other cytokines, helping the body balance its inflammatory response.
Research Applications
Selank is widely utilized in studies focusing on emotional stability and mental performance:
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Anxiety Management: Investigating its role in treating Generalized Anxiety Disorder (GAD) and social anxiety without the “brain fog” typical of traditional medications.
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Focus Under Stress: Studying how the peptide maintains cognitive clarity and memory recall in subjects exposed to high-pressure environments.
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Immune System Support: Researching its antiviral properties and its ability to modulate the immune response during chronic stress.
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Mood Regulation: Investigating its antidepressant-like effects, particularly when paired with its nootropic (cognitive-enhancing) benefits.
Storage and Handling
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Storage: Store the lyophilized powder at 2-8°C. For long-term storage (over 6 months), keeping it at -20°C is recommended.
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Stability: In its dry form, Selank is relatively stable at room temperature for several weeks, but it should be returned to cold storage as soon as possible.
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Reconstitution: Once mixed with bacteriostatic water, it must be stored in the refrigerator at 4°C. It is generally stable for 2–4 weeks in solution, though many research protocols suggest using it within 14 days for peak potency.
Disclaimer: This material is sold for research and development purposes only. It is not intended for human ingestion, diagnostic, therapeutic, or clinical procedures. All research must be conducted by qualified professionals in a laboratory setting.
