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SLU-PP-332 5 mg

SLU-PP-332 5 mg

Original price was: $40.00.Current price is: $33.00.

SLU-PP-332 (5 mg)
SLU-PP-332 is a synthetic research compound explored for its potential effects on cellular metabolism, mitochondrial efficiency, and energy regulation. Supplied as a 5 mg lyophilized powder, this material is intended strictly for laboratory research and in-vitro analysis.
For laboratory research use only. Not for human consumption.

In stock

Estimated delivery dates: Apr 18, 2026 - Apr 21, 2026
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Description

Technical Monograph: S-LUP-332 | Selective Pan-ERR Agonist

Product Code: HRL-SLU-05 | Total Mass: 5 mg

This high-purity small molecule is a potent, selective agonist of the Estrogen-Related Receptors (ERR$alpha$, , and ). Engineered for advanced metabolic research, this 5 mg variant is optimized for investigating the transcriptional regulation of oxidative phosphorylation and the induction of a “high-oxidative” cellular phenotype in vitro.

Molecular Specification & Composition

Attribute Technical Detail
Chemical Name 4-[[2,4-bis(trifluoromethyl)phenyl]methyl]-5-ethyl-1H-pyrrole-2-carboxylic acid
Molecular Formula $C_{16}H_{13}F_6NO_2$
Molecular Weight 365.27 g/mol
Purity (HPLC) >99.0%
Total Mass 5 mg Lyophilized Powder

Analytical Characteristics

  • Nuclear Receptor Agonism: Specifically formulated to bind and activate all three isoforms of the ERR family, which are essential for regulating the expression of genes involved in energy metabolism.

  • Oxidative Flux Modeling: Designed to investigate the upregulation of PGC-1$alpha$ and the subsequent increase in mitochondrial density and oxygen consumption rates.

  • Metabolic Reprogramming Utility: Engineered to observe the shift from glycolytic to oxidative metabolism in specialized skeletal muscle or myocardial cellular models.

Laboratory Application Fields

  1. Mitochondrial Biogenesis Research: Investigating the concurrent activation of the entire mitochondrial gene program in response to ERR agonism.

  2. Bioenergetic Efficiency Studies: Analysis of the compound’s influence on fatty acid -oxidation and glucose utilization in vitro.

  3. Skeletal Muscle Phenotype Modeling: Evaluation of the impact of SLU-PP-332 on the expression of slow-twitch, oxidative fiber-type markers.

  4. Metabolic Syndrome Signaling: Studying the interaction between ERR activation and the modulation of lipid accumulation and insulin sensitivity in adipocyte models.

Storage & Handling Protocols

  • Thermal Management: Store lyophilized powder at -20°C for maximum molecular integrity.

  • Reconstitution: Soluble in DMSO or ethanol for laboratory research. Once in solution, maintain at 2-8°C and protect from direct UV exposure to prevent photodegradation of the pyrrole structure.

  • Stability: This small molecule is highly stable compared to linear peptides but should be handled under sterile conditions to maintain purity.

IMPORTANT NOTICE & DISCLAIMER

FOR LABORATORY RESEARCH USE ONLY. This product is a synthesized chemical reagent intended solely for in vitro laboratory research and analytical testing. It is NOT a drug, food, or cosmetic, and it is NOT intended for human consumption, inhalation, or any form of internal or external application to humans or animals.

Any use of this product outside of a controlled laboratory setting is strictly prohibited. The purchaser assumes all responsibility for the handling, storage, and regulatory compliance of this compound. Hudson Research Lab does not provide medical advice or instructions for human application. Keep out of reach of children.

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