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SELANK 5 MG

SELANK 5 MG

Original price was: $40.00.Current price is: $31.00.

In stock

Estimated delivery dates: Apr 18, 2026 - Apr 21, 2026
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Description

Technical Monograph: S-LNK-05 | Synthetic Heptapeptide Reagent

Product Code: HRL-SEL-05 | Total Peptide Mass: 5 mg

This high-purity synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a stable analog of the endogenous tetrapeptide Tuftsin. Engineered for advanced neurobiological research, this 5 mg variant is optimized for investigating the modulation of the GABAergic system and the inhibition of enkephalin-degrading enzymes in neural cellular models.

Molecular Specification & Composition

Attribute Technical Detail
Sequence Fragment L-Threonyl-L-Lysyl-L-Prolyl-L-Arginyl-L-Prolyl-Glycyl-L-Proline
Molecular Weight 751.9 g/mol
Purity (HPLC) >99.0%
Total Mass 5 mg Lyophilized Powder

Analytical Characteristics

  • Enkephalinase Inhibition Research: Formulated to study the stabilization of endogenous enkephalins by inhibiting the enzymes responsible for their degradation in vitro.

  • GABAergic Modulation Modeling: Specifically designed to investigate the allosteric modulation of receptors and their role in neurotransmission signaling.

  • Metabolic Stability: The addition of the Pro-Gly-Pro sequence to the Tuftsin base ensures superior resistance to peptidases, providing a wider observation window during neuro-signaling simulations.

Laboratory Application Fields

  1. Neurotransmitter Signaling Research: Investigating the balance between excitatory and inhibitory neurotransmission in hippocampal cell lines.

  2. BDNF Expression Studies: Analysis of the peptide’s influence on the mRNA expression of Brain-Derived Neurotrophic Factor in neural models.

  3. Immunomodulatory Pathway Mapping: Studying the interaction between the nervous and immune systems through the tuftsin-like signaling domain.

  4. Enzymatic Degradation Modeling: Evaluation of the peptide’s ability to preserve the structural integrity of endogenous opioid peptides under cellular stress.

Storage & Handling Protocols

  • Thermal Management: Store lyophilized vials at -20°C for maximum molecular integrity.

  • Reconstitution: Maintain at 2-8°C post-reconstitution. This heptapeptide is highly stable in aqueous solution but should be protected from microbial contamination and direct light exposure.

IMPORTANT NOTICE & DISCLAIMER

FOR LABORATORY RESEARCH USE ONLY. This product is a synthesized chemical reagent intended solely for in vitro laboratory research and analytical testing. It is NOT a drug, food, or cosmetic, and it is NOT intended for human consumption, inhalation, or any form of internal or external application to humans or animals.

Any use of this product outside of a controlled laboratory setting is strictly prohibited. The purchaser assumes all responsibility for the handling, storage, and regulatory compliance of this compound. Hudson Research Lab does not provide medical advice or instructions for human application. Keep out of reach of children.

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