Description
Technical Monograph: E-PITH-50 | Pineal-Regulatory Tetrapeptide
Product Code: HRL-EPI-50 | Total Peptide Mass: 50 mg
This high-purity synthetic tetrapeptide (Ala-Glu-Asp-Gly) is a stabilized analog of the endogenous peptide Epithalamin, naturally secreted by the pineal gland. Engineered for advanced geriatric and cellular research, this high-concentration 50 mg variant is optimized for investigating the modulation of chromatin structure and the upregulation of specific enzymatic pathways.
Molecular Specification & Composition
| Attribute | Technical Detail |
| Sequence Fragment | L-Alanyl-L-Glutamyl-L-Aspartyl-Glycine |
| Molecular Weight | 390.3 g/mol |
| Purity (HPLC) | >99.0% |
| Total Mass | 50 mg Lyophilized Powder |
Analytical Characteristics
-
Epigenetic Modulation Research: Formulated to study the induction of telomerase activity and the maintenance of chromosomal structural integrity in vitro.
-
Pineal-Axis Modeling: Specifically designed to investigate the restoration of endogenous melatonin secretion patterns and circadian rhythm signaling.
-
Proteolytic Stability: Vacuum-sealed and lyophilized to maintain the peptide’s carboxyl and amino-terminal integrity during baseline testing.
Laboratory Application Fields
-
Telomerase Activation Studies: Investigating the enzymatic elongation of telomeric repeats in senescent cell populations.
-
Oxidative Stress Modeling: Analysis of the peptide’s influence on superoxide dismutase (SOD) and glutathione peroxidase activity.
-
Circadian Signaling Research: Studying the interaction between pineal-gland-derived peptides and the master biological clock.
-
Chromatin Remodeling: Evaluation of the peptide’s role in “unpacking” condensed DNA segments for gene transcription studies.
Storage & Handling Protocols
-
Thermal Management: Store lyophilized vials at -20°C for maximum molecular integrity.
-
Reconstitution: Maintain at 2-8°C post-reconstitution. This tetrapeptide is highly stable; however, it should be protected from microbial contamination and extreme temperature fluctuations.
IMPORTANT NOTICE & DISCLAIMER
FOR LABORATORY RESEARCH USE ONLY. This product is a synthesized chemical reagent intended solely for in vitro laboratory research and analytical testing. It is NOT a drug, food, or cosmetic, and it is NOT intended for human consumption, inhalation, or any form of internal or external application to humans or animals.
Any use of this product outside of a controlled laboratory setting is strictly prohibited. The purchaser assumes all responsibility for the handling, storage, and regulatory compliance of this compound. Hudson Research Lab does not provide medical advice or instructions for human application. Keep out of reach of children.
