Description
Technical Monograph: S-S31 | Mitochondrial-Targeted Research Reagent
Product Code: HRL-SS-10 / HRL-SS-50 | Total Peptide Mass: 10 mg / 50 mg
This high-purity synthetic tetra-peptide (D-Arg-2′,6′-Dmt-Lys-Phe-NH2) is a specialized laboratory reagent designed for mitochondrial-specific signaling research. Engineered for advanced bioenergetic studies, this variant is optimized for investigating the preservation of the inner mitochondrial membrane and the optimization of the electron transport chain.
Molecular Specification & Composition
| Attribute | Technical Detail |
| Sequence Type | D-Amino Acid Stabilized Tetrapeptide |
| Molecular Weight | 639.8 g/mol |
| Purity (HPLC) | >99.0% |
| Available Mass | 10 mg or 50 mg Lyophilized Powder |
Analytical Characteristics
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Cardiolipin Affinity: Specifically formulated to bind to cardiolipin in the inner mitochondrial membrane, facilitating the stabilization of cristae structure in vitro.
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Electron Transport Chain (ETC) Utility: Designed to investigate the reduction of electron leakage and the optimization of oxidative phosphorylation pathways.
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Structural Stability: The D-amino acid configuration ensures superior resistance to peptidases, providing high metabolic stability in various cellular research media.
Laboratory Application Fields
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Mitochondrial Bioenergetics: Investigating the upregulation of ATP synthesis and the modulation of oxygen consumption rates.
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Oxidative Stress Research: Analysis of the peptide’s influence on the localized production of reactive oxygen species (ROS) within the mitochondria.
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Ischemia-Reperfusion Modeling: Studying the impact of mitochondrial membrane stabilization on cellular recovery following oxygen deprivation simulations.
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Neurodegenerative Signaling: Evaluation of the peptide’s role in protecting mitochondrial integrity in specialized neural cell lines.
Storage & Handling Protocols
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Thermal Management: Store lyophilized vials at -20°C for maximum molecular integrity.
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Reconstitution: Maintain at 2-8°C post-reconstitution. This peptide is highly stable due to its D-amino acid structure; however, it should be protected from microbial contamination and extreme pH shifts.
IMPORTANT NOTICE & DISCLAIMER
FOR LABORATORY RESEARCH USE ONLY. This product is a synthesized chemical reagent intended solely for in vitro laboratory research and analytical testing. It is NOT a drug, food, or cosmetic, and it is NOT intended for human consumption, inhalation, or any form of internal or external application to humans or animals.
Any use of this product outside of a controlled laboratory setting is strictly prohibited. The purchaser assumes all responsibility for the handling, storage, and regulatory compliance of this compound. Hudson Research Lab does not provide medical advice or instructions for human application. Keep out of reach of children.
