Description
Technical Monograph: GHR-P2 | Second-Gen GHS Receptor Agonist
Product Code: HRL-G2-05 / HRL-G2-15 | Total Peptide Mass: 5 mg / 15 mg
This high-purity hexapeptide is a potent synthetic agonist of the Growth Hormone Secretagogue Receptor (GHS-R1a). Engineered for endocrine research, this variant is optimized for investigating the amplified pulsatile secretion of somatotropic signaling molecules with a more selective metabolic profile than first-generation analogs.
Molecular Specification & Composition
| Attribute | Technical Detail |
| Sequence Fragment | D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2 |
| Molecular Weight | 817.9 g/mol |
| Purity (HPLC) | >99.0% |
| Available Mass | 5 mg or 15 mg Lyophilized Powder |
Analytical Characteristics
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Enhanced GHS-R1a Selectivity: Specifically designed to trigger a more robust release of endogenous GH compared to earlier analogs while maintaining moderate impact on secondary axes.
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Potency Calibration: Formulated for high-resolution data collection in dose-response studies, allowing researchers to observe the saturation limits of pituitary receptor sites.
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Structural Stability: Vacuum-sealed and lyophilized to preserve the D-amino acid configuration, ensuring high resistance to enzymatic degradation during baseline testing.
Laboratory Application Fields
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Somatotropic Pulse Modeling: Investigating the amplitude and frequency of hormone secretion under various synthetic stimuli.
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Pituitary Receptor Saturation: Analysis of the dose-dependent response curves of GHS-R1a activation in vitro.
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Metabolic Efficiency Research: Studying the impact of secretagogue-mediated signaling on nitrogen balance and protein turnover.
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Endocrine Cross-Talk Studies: Evaluating the moderate influence of the peptide on ACTH and prolactin levels in isolated biological systems.
Storage & Handling Protocols
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Thermal Management: Store lyophilized vials at -20°C for maximum molecular integrity.
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Reconstitution: Maintain at 2-8°C post-reconstitution. This hexapeptide is highly stable; however, it should be protected from contamination and extreme pH environments.
IMPORTANT NOTICE & DISCLAIMER
FOR LABORATORY RESEARCH USE ONLY. This product is a synthesized chemical reagent intended solely for in vitro laboratory research and analytical testing. It is NOT a drug, food, or cosmetic, and it is NOT intended for human consumption, inhalation, or any form of internal or external application to humans or animals.
Any use of this product outside of a controlled laboratory setting is strictly prohibited. The purchaser assumes all responsibility for the handling, storage, and regulatory compliance of this compound. Hudson Research Lab does not provide medical advice or instructions for human application. Keep out of reach of children.
