Description
Technical Monograph: GHR-P6 | Selective GHS Receptor Agonist
Product Code: HRL-G6-05 / HRL-G6-10 | Total Peptide Mass: 5 mg / 10 mg
This high-purity hexapeptide is a first-generation synthetic agonist of the Growth Hormone Secretagogue Receptor (GHS-R1a). Engineered for endocrine and metabolic research, this variant is optimized for investigating the pulsatile secretion of somatotropic signaling molecules and the modulation of the ghrelin-receptor pathway.
Molecular Specification & Composition
| Attribute | Technical Detail |
| Sequence Fragment | His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 |
| Molecular Weight | 873.0 g/mol |
| Purity (HPLC) | >99.0% |
| Available Mass | 5 mg or 10 mg Lyophilized Powder |
Analytical Characteristics
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GHS-R1a Affinity: Specifically designed to mimic the action of endogenous ghrelin, triggering the downstream activation of the pituitary gland in vitro.
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Metabolic Signaling Utility: Formulated to study the activation of the hypothalamic arcuate nucleus, allowing for data collection on energy balance and nutrient partitioning.
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Sequence Fidelity: HPLC-verified to ensure zero degradation of the D-amino acid configuration, providing superior stability during baseline testing compared to linear analogs.
Laboratory Application Fields
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Somatotropic Axis Research: Investigating the pulse frequency of growth hormone secretion when stimulated by a synthetic secretagogue.
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Ghrelin-Mimetic Modeling: Analysis of the peptide’s influence on gastric motility and orexigenic signaling in metabolic models.
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Protective Signaling Studies: Evaluation of the peptide’s potential role in cytoprotection and cardiac-tissue signaling in isolated biological samples.
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Nitrogen Retention Research: Studying the impact of GHS-R activation on protein turnover and amino acid transport at the cellular level.
Storage & Handling Protocols
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Thermal Management: Store lyophilized vials at -20°C for maximum molecular integrity.
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Reconstitution: Maintain at 2-8°C post-reconstitution. This hexapeptide is relatively stable but should be protected from extreme pH shifts or direct sunlight.
IMPORTANT NOTICE & DISCLAIMER
FOR LABORATORY RESEARCH USE ONLY. This product is a synthesized chemical reagent intended solely for in vitro laboratory research and analytical testing. It is NOT a drug, food, or cosmetic, and it is NOT intended for human consumption, inhalation, or any form of internal or external application to humans or animals.
Any use of this product outside of a controlled laboratory setting is strictly prohibited. The purchaser assumes all responsibility for the handling, storage, and regulatory compliance of this compound. Hudson Research Lab does not provide medical advice or instructions for human application. Keep out of reach of children.
