Description
Technical Monograph: G-COP | Copper-Tripeptide Chelate
Product Code: HRL-GHK-50 / HRL-GHK-100 | Total Peptide Mass: 50 mg / 100 mg
This high-purity synthetic tripeptide (Glycyl-L-Histidil-L-Lysine) is complexed with a copper (II) ion. Engineered for advanced dermal and cellular research, this high-concentration variant is optimized for investigating the upregulation of structural proteins and the modulation of the extracellular matrix (ECM) through specific ionic-peptide signaling pathways.
Molecular Specification & Composition
| Attribute | Technical Detail |
| Sequence Fragment | Gly-His-Lys (GHK) |
| Metal Complex | Copper (II) Ion ($Cu^{2+}$) |
| Molecular Weight | 402.5 g/mol |
| Purity (HPLC) | >99.0% |
| Available Mass | 50 mg or 100 mg Lyophilized Powder |
Analytical Characteristics
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Ionic Binding Stability: Optimized copper-peptide chelation ensures high stability during aqueous reconstitution, resulting in a characteristic blue spectrum.
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ECM Upregulation Research: Formulated to study the “feedback loop” that triggers the synthesis of Collagen I, III, and IV, as well as glycosaminoglycans in vitro.
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Fibroblast Activation Utility: Designed to investigate the stimulation of dermal fibroblasts and the modulation of the inflammatory cascade through copper-dependent pathways.
Laboratory Application Fields
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Extracellular Matrix (ECM) Modeling: Investigating the concurrent upregulation of structural proteins and the organization of the fiber network.
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Angiogenesis Research: Analysis of the peptide’s influence on vascular endothelial growth factor (VEGF) expression in cellular models.
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DNA Damage Repair Studies: Evaluation of the peptide’s role in protecting cellular integrity and modulating antioxidant enzyme activity (SOD).
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Follicular Signaling Research: Studying the interaction between copper-peptides and the localized cellular environment in isolated hair follicle models.
Storage & Handling Protocols
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Thermal Management: Store lyophilized vials at -20°C for maximum molecular integrity.
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Reconstitution: Maintain at 2-8°C post-reconstitution. Upon addition of a diluent, the solution will turn deep blue; this is a normal characteristic of the copper chelation.
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Handling: Protect from direct UV exposure and high-frequency agitation, which can degrade the peptide-metal bond.
IMPORTANT NOTICE & DISCLAIMER
FOR LABORATORY RESEARCH USE ONLY. This product is a synthesized chemical reagent intended solely for in vitro laboratory research and analytical testing. It is NOT a drug, food, or cosmetic, and it is NOT intended for human consumption, inhalation, or any form of internal or external application to humans or animals.
Any use of this product outside of a controlled laboratory setting is strictly prohibited. The purchaser assumes all responsibility for the handling, storage, and regulatory compliance of this compound. Hudson Research Lab does not provide medical advice or instructions for human application. Keep out of reach of children.
