Description
Technical Monograph: H-EXA-05 | High-Selectivity GHS Receptor Agonist
Product Code: HRL-HEX-05 | Total Peptide Mass: 5 mg
This high-purity hexapeptide is a potent synthetic agonist of the Growth Hormone Secretagogue Receptor (GHS-R1a). Engineered for advanced endocrine and cardiovascular research, this 5 mg variant is optimized for investigating the maximal pulsatile secretion of somatotropic signaling molecules and the modulation of protective pathways in myocardial cellular models.
Molecular Specification & Composition
| Attribute | Technical Detail |
| Sequence Fragment | His-D-2-Me-Trp-Ala-Trp-D-Phe-Lys-NH2 |
| Molecular Weight | 887.0 g/mol |
| Purity (HPLC) | >99.0% |
| Total Mass | 5 mg Lyophilized Powder |
Analytical Characteristics
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High-Efficiency Receptor Binding: Specifically designed to trigger a robust GH release, often exceeding the peak amplitudes seen with other secretagogues in comparative signaling studies.
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Non-Orexigenic Profile: Unlike other GHS-R agonists, Hexarelin is studied for its ability to activate the pituitary axis without significantly stimulating the hunger-signaling pathways of the ghrelin receptor.
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Structural Stability: Vacuum-sealed and lyophilized to preserve the D-amino acid configuration, ensuring high resistance to enzymatic degradation during baseline testing.
Laboratory Application Fields
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Somatotropic Peak Modeling: Investigating the absolute ceiling of growth hormone secretion when subjected to a potent synthetic secretagogue.
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Cardiocyte Signaling Research: Analysis of the peptide’s influence on CD36 and GHS-R receptors located within cardiovascular tissue models.
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Cytoprotective Studies: Evaluating the peptide’s role in protecting cellular integrity during induced oxidative stress or nutrient deprivation simulations.
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Pituitary Desensitization Research: Studying the “refractory period” and receptor downregulation when exposed to high-potency ligands.
Storage & Handling Protocols
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Thermal Management: Store lyophilized vials at -20°C for maximum molecular integrity.
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Reconstitution: Maintain at 2-8°C post-reconstitution. This peptide is highly potent; ensure precise calibration of dilution ratios for high-fidelity data collection.
IMPORTANT NOTICE & DISCLAIMER
FOR LABORATORY RESEARCH USE ONLY. This product is a synthesized chemical reagent intended solely for in vitro laboratory research and analytical testing. It is NOT a drug, food, or cosmetic, and it is NOT intended for human consumption, inhalation, or any form of internal or external application to humans or animals.
Any use of this product outside of a controlled laboratory setting is strictly prohibited. The purchaser assumes all responsibility for the handling, storage, and regulatory compliance of this compound. Hudson Research Lab does not provide medical advice or instructions for human application. Keep out of reach of children.
